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Teaching

Nigerian Virtual Pathology Project - 2017 - TSL EQA Workshop (November)







Case 1

Male 44 years

Non-ulcerated solitary circumscribed scalp nodule.


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Case 2

Female 56 years

Forehead ulcerated hyperpigmented nodule.


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Case 3

Female 25 years

Mons pubis swelling/mass.


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Case 4

Female 40 years

Vulva growth, labial mass.


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Case 5



Suprapubic warts extending to lower abdomen.


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Case 6

Female 61 years

Forearm and palm warty hyperpigmented rashes.


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Case 7



Leg mass, adult.


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Case 8

Male 70 years

Recurrent knee mass,? Incomplete initial excision of a circumscribed lesion.


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Case 9

Female 13 years

Nodular lesion on the cheek.


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Case 10

Male 36 years

Skin nodule side of foot.


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Case 11

Female 65 years

Pigmented lesion plantar aspect of left foot.


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Case 12

Male 43 years

Mole (?malignant melanoma) from abdomen.


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Case 13

Male 79 years

Mole (?malignant melanoma) excised from the epigastrium.


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Case 14

Male 73 years

Lesion left elbow ? keratoacanthoma.


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Case 15

Female 34 years

Tender lump side of terminal phalanx right little finger. Lesional cells express SMA and CD34 in a strong uniform manner but are negative with S100 and cytokeratins.


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Case 16

Female 64 years

Right wrist papule present for a few years.


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Case 17

Male 18 years

Lesion right side of chest.


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Case 18



Adult male with mass in left inguinal region. Lesional cells have strong uniform expression of CD34 but are negative with S100, Desmin and CD31.


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CD34
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Desmin
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S100
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Case 19

Female 3 years

Right upper lid mass of 2 months duration. Lesional cells have strong uniform expression of desmin and sarcomeric actin but are negative with S100 and AE1/3 (cytokeratins).


Case 20

Female 54 years

Abdominal swelling of 10 yrs. Solid cystic right ovarian mass found at operation. Tumour cells express CD56 but are negative with WT-1 and GCDFP-15.


Case 21

Male 48 years

Lymph node excision biopsy (site not specified). Tumour cells express AE1/3 (cytokeratins) and Hep Par 1 but are negative with S100.


Case 22

Male 25 years

Retroperitoneal tumour 21 x 15 x 15 cm tightly covered by sigmoid/transverse colon mesentery. Tumour cells have strong uniform expression of CD34 but are completely negative with S100, EMA, desmin, AE1/3 (cytokeratins), CD117 and DOG-1. Ki-67 index = 1%.


Case 23

Male 63 years

Upper abdominal swelling gradually increasing in size for 4yrs. Early satiety and weight loss. No constipation or vomiting. Intra-op finding of solid mass 30 x 30 20 cm arising from lesser curvature of stomach. Tumour cells express CD34, CD117 and DOG-1 with a Ki-67 index of 1%. They are negative with S100 and desmin.


Case 24

Male 31 years

Left popliteal soft tissue mass. Patchy strong expression of S100 by tumour cells which are completely negative for cytokeratins (AE1/3) and CD31.


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S100
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CD31
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Case 25

Male 70 years

Excision of previously (histologically diagnosed) DFSP (site not stated). Tumour cells have strong uniform expression of CD34 and very focal/patchy expression of S100 in a small minority of cells. They are negative with desmin EMA, NFP and broad spectrum cytokeratins (AE1/3).


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CD34
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S100
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Desmin
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