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Teaching

Biomedical Sciences - PRINCIPLES OF DISEASE





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Week 10

Lecture outline

Interesting host-tumour interactions involved in invasion and metastasis will be described. Also how we describe the point on the journey the tumour has reached (stage) and how much further it is likely to go (prognosis). We will also describe the methods used to judge how quickly the tumour is travelling along the pathway (grade).

Behaviour of Tumours 2

Created by Prof. Mike Dixon

Female age 64

Tissue: Bone

This previously fit woman developed acute pain in the left hip but had no history of a fall or other trauma. On examination there was slight bruising over the lateral aspect of her upper thigh but no signs of a fractured neck of femur (leg shortening or external rotation). Nevertheless she was sent for X-rays and these revealed a non-displaced fracture through a tumour. After further investigations she underwent surgical resection. What is the nature of the tumour (Diagnosis 1)? What do you call a fracture caused by a tumour in the bone (Diagnosis 2)?

The cut surface of the femur shows a tumour occupying the proximal end and a band of haemorrhage across it marking the site of the fracture.


 MFD1015g.jpg

1099


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