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Teaching

Biomedical Sciences - PRINCIPLES OF DISEASE





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Week 5

Lecture outline

Infectious diseases are the commonest overall cause of death worldwide. The first lecture will introduce the students to the types of micro-organism found in health and disease, and describe basic methods of classification. The second lecture will describe the micro-organisms found in health (normal flora). The subsequent clinical symposium will demonstrate the ways in which these micro-organisms can cause disease, and the impact of such disease.

Microbiology 1

Created by Prof. Mike Dixon

Female age 59

Tissue: Stomach

This patient had a long history of 'dyspepsia' - indigestion. More recently she had developed sustained upper abdominal pain and 3 days prior to admission she began to vomit blood. She underwent endoscopy where a bleeding ulcer was seen in the gastric antrum. She underwent an emergency partial gastrectomy. The slide is taken from a slice of tissue through the ulcer. Examine the gastric mucosa at the sides of the ulcer. Taken in conjunction with the Giemsa-stained slide, what is the diagnosis?

This is a high power view of the surface epithelium of the stomach. Using a special stain (a modified Giemsa stain) large numbers of slightly spiral or curved bacteria can be seen.


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1487


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