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Teaching

Biomedical Sciences - PRINCIPLES OF DISEASE





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Week 7

Lecture outline

The vascular topics are concluded with descriptions of the pathological processes of thrombosis, embolism, infarction, hypertension and heart failure. These are very common events that need to be understood.

Ischaemia 4

Created by Prof. Mike Dixon

Male age 52

Tissue: Heart - myocardium

This moderately obese man was admitted to hospital 5 hours after the onset of severe central chest pain. After initial assessment he was transferred to the Coronary Care Unit. Two days later his blood pressure dropped to very low levels and he was treated for cardiogenic shock. Despite intensive treatment he failed to respond and his general condition steadily deteriorated. He died 5 days after admission.

This is the posterior aspect of the heart. The pericardial covering is inflamed, appearing haemorrhagic and granular due to the presence of a thin fibrinous exudate. The underlying muscle contains areas of haemorrhage.


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